GABA_BResponseODE Class Reference

#include <GABA_BResponseODE.h>

Inheritance diagram for GABA_BResponseODE:

Collaboration diagram for GABA_BResponseODE:

List of all members.

Public Member Functions

GABA_BResponseODE ()

virtual ~GABA_BResponseODE ()

virtual int reset (double dt)

Called at the beginning of a simulation at t=0.

virtual void derivatives (double t, const double y[], double f[])

virtual int advance (AdvanceInfo const &ai)

Calculate the next state and output/propagate the result to succesors/outgoing objects.

virtual int spikeHit (spikeport_t port, SpikeEvent const &spike)

virtual int psrLength (double dt) const

The lengh of the postsynaptic response (in time steps).

Public Attributes

double k1

Binding rate for transmitter substance in the cleft to receptors [range=(0,1); units=ms^-1;].

double k2

Unbinding rate for the transmitter substance to the receptors.

double k3

Binding rate for the G-proteins to the K+ channel.

double k4

Unbinding rate for the G-proteins to the K+ channel.

double kd

Dissociation constant of binding G-protein to K+ channels.

double Cmax

max. amount of Transmitter in the synaptic cleft

double Cdur

Transmitter duration.

double dead_time

min. time between release events

int n

Number of individual binding sites for the G-protein in a singel K+ channel.

double r

Fraction of activated receptors.

double s

Concentration of G-proteins binded to K+ channels.

double C

double time_count

double g_max

Protected Member Functions

int init ()

Protected Attributes

odeiv::Solver * solver

A solver for the differential equations.

double y [2]

Detailed Description

Definition at line 12 of file GABA_BResponseODE.h.

Constructor & Destructor Documentation

GABA_BResponseODE::GABA_BResponseODE ( )

Definition at line 4 of file GABA_BResponseODE.cpp.

References Cdur, Cmax, dead_time, k1, k2, k3, k4, kd, n, and solver.

GABA_BResponseODE::~GABA_BResponseODE ( ) [virtual]

Definition at line 21 of file GABA_BResponseODE.cpp.

References solver.

Member Function Documentation

int GABA_BResponseODE::reset ( double dt ) [virtual]

Called at the beginning of a simulation at t=0.

Reimplemented from FiniteSpikeResponse.

Definition at line 37 of file GABA_BResponseODE.cpp.

References C, dead_time, init(), FiniteSpikeResponse::psr, r, FiniteSpikeResponse::reset(), odeiv::Solver::reset(), s, solver, time_count, and y.

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void GABA_BResponseODE::derivatives	(	double	t,
		const double	y[],
		double	f[]
	)			`[virtual]`

Implements odeiv::ODESystem.

Definition at line 61 of file GABA_BResponseODE.cpp.

References C, k1, k2, k3, k4, r, s, solver, and odeiv::Solver::y().

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int GABA_BResponseODE::advance ( AdvanceInfo const & ) [virtual]

Calculate the next state and output/propagate the result to succesors/outgoing objects.

The return value of advance contains several bits of information which can be decoded with the bit masks ADVANCEFLAG_* like ADVANCEFLAG_HASSPIKED and ADVANCEFLAG_DEACTIVATE.

Reimplemented from SimObject.

Reimplemented in GenericConductanceBasedSpikingSynapse< GABA_BResponseODE >.

Definition at line 75 of file GABA_BResponseODE.cpp.

References odeiv::Solver::advance(), FiniteSpikeResponse::advanceReturn(), C, AdvanceInfo::dt, g_max, Time::in_sec(), kd, n, FiniteSpikeResponse::psr, r, s, solver, AdvanceInfo::t, time_count, and odeiv::Solver::y().

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int GABA_BResponseODE::spikeHit	(	spikeport_t	port,
		SpikeEvent const &	spike
	)			`[virtual]`

Function to be called if the object is hit by a spike Called by spike exchange mechanims if a spike hits (arrives at) the object A return value of greater 0 indicates that the object is currently not active and the sim engine has to put this object into its list of active spike receivers. A return value of 0 indicates the the object is currently active (i.e. is already in the list of active receviers) and need not to be put into the list of active synapses.

Reimplemented from SimObject.

Reimplemented in GenericStaticSpikingSynapse< GenericConductanceBasedSpikingSynapse< GABA_BResponseODE > >.

Definition at line 93 of file GABA_BResponseODE.cpp.

References C, Cdur, Cmax, dead_time, SpikeEvent::dt, FiniteSpikeResponse::spikeHitReturn(), and time_count.

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int GABA_BResponseODE::psrLength ( double dt ) const [virtual]

The lengh of the postsynaptic response (in time steps).

Implements FiniteSpikeResponse.

Definition at line 110 of file GABA_BResponseODE.cpp.

References PSR_MULTIPLE_TAU.

int GABA_BResponseODE::init ( ) [protected]

Definition at line 28 of file GABA_BResponseODE.cpp.

References odeiv::ODESystem::setSystem(), and solver.

Referenced by reset().

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Member Data Documentation

double GABA_BResponseODE::k1

Binding rate for transmitter substance in the cleft to receptors [range=(0,1); units=ms^-1;].

Definition at line 19 of file GABA_BResponseODE.h.

Referenced by derivatives(), GABA_BResponseODE(), and GABA_BSynapseODE::GABA_BSynapseODE().

double GABA_BResponseODE::k2

Unbinding rate for the transmitter substance to the receptors.

Definition at line 21 of file GABA_BResponseODE.h.

Referenced by derivatives(), GABA_BResponseODE(), and GABA_BSynapseODE::GABA_BSynapseODE().

double GABA_BResponseODE::k3

Binding rate for the G-proteins to the K+ channel.

Definition at line 24 of file GABA_BResponseODE.h.

Referenced by derivatives(), GABA_BResponseODE(), and GABA_BSynapseODE::GABA_BSynapseODE().

double GABA_BResponseODE::k4

Unbinding rate for the G-proteins to the K+ channel.

Definition at line 26 of file GABA_BResponseODE.h.

Referenced by derivatives(), GABA_BResponseODE(), and GABA_BSynapseODE::GABA_BSynapseODE().

double GABA_BResponseODE::kd

Dissociation constant of binding G-protein to K+ channels.

Definition at line 29 of file GABA_BResponseODE.h.

Referenced by advance(), GABA_BResponseODE(), and GABA_BSynapseODE::GABA_BSynapseODE().

double GABA_BResponseODE::Cmax

max. amount of Transmitter in the synaptic cleft

Definition at line 32 of file GABA_BResponseODE.h.

Referenced by GABA_BResponseODE(), GABA_BSynapseODE::GABA_BSynapseODE(), and spikeHit().

double GABA_BResponseODE::Cdur

Transmitter duration.

Definition at line 35 of file GABA_BResponseODE.h.

Referenced by GABA_BResponseODE(), GABA_BSynapseODE::GABA_BSynapseODE(), and spikeHit().

double GABA_BResponseODE::dead_time

min. time between release events

Definition at line 38 of file GABA_BResponseODE.h.

Referenced by GABA_BResponseODE(), GABA_BSynapseODE::GABA_BSynapseODE(), reset(), and spikeHit().

int GABA_BResponseODE::n

Number of individual binding sites for the G-protein in a singel K+ channel.

Definition at line 41 of file GABA_BResponseODE.h.

Referenced by advance(), GABA_BResponseODE(), and GABA_BSynapseODE::GABA_BSynapseODE().

double GABA_BResponseODE::r

Fraction of activated receptors.

Definition at line 44 of file GABA_BResponseODE.h.

Referenced by advance(), derivatives(), and reset().

double GABA_BResponseODE::s

Concentration of G-proteins binded to K+ channels.

Definition at line 47 of file GABA_BResponseODE.h.

Referenced by advance(), derivatives(), and reset().

double GABA_BResponseODE::C

Definition at line 61 of file GABA_BResponseODE.h.

Referenced by advance(), derivatives(), reset(), and spikeHit().

double GABA_BResponseODE::time_count

Definition at line 63 of file GABA_BResponseODE.h.

Referenced by advance(), reset(), and spikeHit().

double GABA_BResponseODE::g_max

Definition at line 65 of file GABA_BResponseODE.h.

Referenced by advance(), and GABA_BSynapseODE::GABA_BSynapseODE().

odeiv::Solver* GABA_BResponseODE::solver [protected]

A solver for the differential equations.

Definition at line 71 of file GABA_BResponseODE.h.

Referenced by advance(), derivatives(), GABA_BResponseODE(), init(), reset(), and ~GABA_BResponseODE().

double GABA_BResponseODE::y[2] [protected]

Definition at line 73 of file GABA_BResponseODE.h.

Referenced by reset().

The documentation for this class was generated from the following files:

/home/tnatschl/PCSIM-Sandbox/pcsim/pcsim/simobjects/GABA_BResponseODE.h
/home/tnatschl/PCSIM-Sandbox/pcsim/pcsim/simobjects/GABA_BResponseODE.cpp


Public Member Functions
	GABA_BResponseODE ()
virtual	~GABA_BResponseODE ()
virtual int	reset (double dt)
	Called at the beginning of a simulation at t=0.
virtual void	derivatives (double t, const double y[], double f[])
virtual int	advance (AdvanceInfo const &ai)
	Calculate the next state and output/propagate the result to succesors/outgoing objects.
virtual int	spikeHit (spikeport_t port, SpikeEvent const &spike)
virtual int	psrLength (double dt) const
	The lengh of the postsynaptic response (in time steps).
Public Attributes
double	k1
	Binding rate for transmitter substance in the cleft to receptors [range=(0,1); units=ms^-1;].
double	k2
	Unbinding rate for the transmitter substance to the receptors.
double	k3
	Binding rate for the G-proteins to the K+ channel.
double	k4
	Unbinding rate for the G-proteins to the K+ channel.
double	kd
	Dissociation constant of binding G-protein to K+ channels.
double	Cmax
	max. amount of Transmitter in the synaptic cleft
double	Cdur
	Transmitter duration.
double	dead_time
	min. time between release events
int	n
	Number of individual binding sites for the G-protein in a singel K+ channel.
double	r
	Fraction of activated receptors.
double	s
	Concentration of G-proteins binded to K+ channels.
double	C
double	time_count
double	g_max
Protected Member Functions
int	init ()
Protected Attributes
odeiv::Solver *	solver
	A solver for the differential equations.
double	y [2]