00001
00005 #ifndef _IONBUFFER_H_
00006 #define _IONBUFFER_H_
00007
00008 #include "ionchannel.h"
00009
00010 #define FARADAY 96589 // Faraday constant [Coulomb]
00011 #define R 8.31 // universal gas constant [Joules/Mol]
00012 #define DEPTH 0.1e-6 // thickness of the intracellular perimembrane shell [m]
00013
00014 #define V_REST_BIOL -70e-3 // [V]
00015 #define V_THRESH_BIOL -40e-3 // [V]
00016
00017 class IonChannel;
00018
00020
00023 class IonBuffer {
00024
00025 public:
00026
00027 IonBuffer(float ConcRest_def, float ConcOut_def, float Tau_def, float Temp_def, int zIon_def);
00028
00029 virtual ~IonBuffer();
00030
00032 void reset(double *Gtot, double *Ich, double Vresting, double VmScale);
00033
00035 void nextstate(double *Imtot, double *Gmtot, double Vm, double Vresting, double VmScale);
00036
00038 void getConc(double **C) { ConcActive = 1; (*C) = &(this->Conc);}
00039
00041 void getErev(double **E) { ConcActive = 1; ErevActive = 1; (*E) = &(this->Erev);}
00042
00044 float ConcRest;
00045
00047 float ConcOut;
00048
00050 float ConcScale;
00051
00053 float Tau;
00054
00056 float Temp;
00057
00058 protected:
00059 friend class MembranePatch;
00060
00061
00063 double Conc;
00064
00066 double Erev;
00067
00069 bool active;
00070
00072 bool ConcActive;
00073
00075 bool ErevActive;
00076
00078 int zIon;
00079
00081 double C1;
00082
00084 int nChannels;
00085
00087 int lChannels;
00088
00090 IonChannel **channels;
00091
00093 void addChannel(IonChannel *newChannel);
00094
00096 void SetErev(double Vresting, double VmScale);
00097
00098 };
00099
00100 #endif
